What Are the Types of Vitamin K Antagonist Anticoagulants ? – Healthcare

What Are the Types of Anticoagulants?

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Anticoagulants are medicines that help prevent your blood from clotting or “beating.”
Your body needs to be able to thicken to help close wounds inside and out of your body.
But unnecessary clots can cause life-threatening complications.
Those that go to the brain can cause a stroke; in the heart, the binding of the heart; and in the lungs, pulmonary embolism.

Although they are sometimes called “blood thinners,” anticoagulants do not actually make your blood. They simply disrupt your body’s natural ability to coagulate.
Different drugs work in different parts of this thickening process.

There are three main types of anticoagulant drugs:

  • Vitamin K antagonists
  • Direct Oral Anticoagulants (DOACs)
  • Low molecular weight heparin (LMWH)
  • hydrochlorothiazide

Vitamin K Antagonist Anticoagulants

Vitamin K helps your blood to thicken. You get it from green leafy vegetables like broccoli and spinach and bacterial action in your gut. Vitamin K “antagonists” like warfarin block your liver from processing vitamin K into “components” that often help to thicken your blood. This prevents blood clotting.

If you are taking this type of medication, it is important to keep the amount of vitamin K in your diet steady so that your doctor can prescribe the right amount of warfarin daily and weekly.
You will receive a blood test so that your doctor can track the effects of your dose and diet. Your doctor will likely use an international standard test, or INR, to check your blood pressure.
One of the potential benefits of this type of anticoagulant is that it is easier than others to recover in the event of sudden bleeding due to injury or emergency surgery.

Direct Oral Anticoagulants (DOACs)

DOACs work much faster than vitamin K antagonists, which have been around for a long time.
DOACs can also be better predicted. So you may not need to have a blood test and be aware of how much you eat and drink vitamin K.
On the other hand, these drugs usually work for a shorter period of time, so you may need to take them twice a day, compared to once a day with other anticoagulants.

DOACs include:

Direct thrombin inhibitors: These drugs interfere with your body’s use of thrombin, a key enzyme that helps to thicken your blood. Although it is usually injected under the skin, you can take it in pill form like dabigatran (Pradaxa).

Direct factor Xa inhibitors: This type of anticoagulant stops the Xa factor in the freezing process from working properly. These drugs, which come in the form of pills, include apixaban (Eliquis), betrixaban (Bevyxxa), edoxaban (Lixiana, Savaysa), and rivaroxaban (Xarelto).

Low Molecular Weight Heparin (LMWH) Anticoagulants
You may know these medications as dalteparin (Fragmin) or enoxaparin (Lovenox).

Compared to the standard undiagnosed heparin (UFH), commonly used in hospitals, LMWH is highly predictable and long-lasting, meaning your doctor does not need to monitor its effects closely like other anticoagulants such as warfarin and UFH.

Doctors prescribe a fixed-dose based on your weight. This medicine is injected under your skin.

You can take both for a while as your doctor closely monitors your reaction to these medications. Then, when your warfarin levels are high enough, you stop LMWH shooting.

Tell your doctor about any nonsteroidal anti-inflammatory drugs (NSAIDs) you are taking, as this may increase the risk of bleeding if you take heparin. NSAIDs are painkillers that include aspirin, ibuprofen, and naproxen.

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